2012 Seminars on Cartilage Repair Scheduled

March 1, Boston, MA

March 22 Ft. Worth TX

March 28 Syracuse NY

Please contact your Zimmer representattive to attend.

Commentary on Clinical Trials in SCIENCE Magazine 12/9/11

In this edition of SCIENCE Dr. Marcus has written a commentary on a previous editorial by Mr. Andy Grove concerning the use of data mining as an improved method of performing clinical trials.

Currently, new medical devices or pharmaceuticals or put through extensive, costly, and often large “comparative” trials in which one group of patients is treated with an old method; the purpose is to both assess safety and efficacy of the new method/drug as compared to the old.

This procedure is already inappropriate for many “orphan” diseases, or situations in which no comparator exists.

In the future, as specific diseases are matched to the patient’s genome- and we find, for example, that cancers are really different in differing patients – establishing such large groups as we have done in the past may no longer be possible.  In effect, each patient may become his/her own control.

Please read the entire thread in SCIENCE if you are interested in differing opinions on this topic.

Click here for Dr. Marcus’ letter.

Dr. Marcus to lecture at the Andrews-Paulos Research Institute Dec 15

Dr. Marcus to have e clinical letter published in SCIENCE Magazine

In December, Science magazine will publish my comments on the role of clinical trials and how they might be changed given the advancements of the information age and the requirements of “personalized medicine”.  It will not longer be sufficient, IMO, to conduct mass market trials that assume all patients are similar. This letter was written in response to a recent editorial on the subject by Andy Grove, former CEO of INTEL.

Dr. Marcus participates in Global Venture Course for Johns Hopkins

Johns Hopkins recently hosted a novel online course for the Australian Biotech Association on Global Perspectives in Biotech Funding; Dr. Marcus was please to participate as one of two invited experts.

Upcoming Cartilage Seminars

November 10; Evansville Indiana

December 1: Providence R.I.

December 8: Manchester N.H.

December 15; Pensacola Fla

Dr. Marcus to Lecture at George Mason University

On November 7 Dr. Marcus will be lecturing at George Mason University, Fairfax, Virginia, Department of

Bioengineering, on the subject of “Tissue Engineering of Cartilage”

Dr. Marcus lectures at Spartanburg Hospital on PRP

On April 28 2011 Dr. Marcus presented at Spartanburg Hospital, Spartanburg, S.C. cases studies pertinent to the use of platelet rich plasma for treatment of tendinopathy and osteoarthritis. This hospital has an advanced blood utilization program that uses PRP for hemostasis and wound healing in total joint surgery, enabling them to significantly lower complications from surgery and reduce length of stay.

Dr. Marcus Performs First Chondrofix Implant on East Coast

Dr. Marcus performs the first Chondrofix Implant on the East Coast. Chondrofix, a new tissue allograft product from Zimmer, Inc, is designed for single stage reconstruction of cartilage defects. It is designed for earlier weight bearing than other cartilage repair techniques and has the advantage of a long shelf life product, being instantly available when needed.